Outline and Evaluate one or more biologic explanation of Schizophrenia (25 marks) The biological approach assumes that Schizophrenia is caused by genetic predisposition and/or chemical imbalances. The dopamine dead reckoning suggests that dopamine over- exertion causes Schizophrenia. Wise & Stein (1973) proposed that a inadequacy of the enzyme that converts dopamine to noradrenaline causes Schizophrenia. This results in too much dopamine and non enough norepinephrine. This is a believable theory because norepinephrine is hint in the brains reward system; so low levels of norepinephrine in the reward centre of the hypothalamus whitethorn lead to a malfunctioning of the reinforcement system, which could cipher for symptoms of Anhedonia. Anhedonia is the inability to feel sport from activities or events that normally cause pleasure. More evidence in support of this model comes from findings that catecholamine, such as dopamine and norepinephrine, looking up certain cognitive functions. For example, Foote et al., (1975) found that application of norepinephrine to the cells in the auditory cortex of squirrel monkeys increased the rate of run of excitant specific cells (neurons that are firing in solution to a real sound) relative to cathode-ray oscilloscope cell activity.

This could level for the auditory hallucinations experienced by those with Schizophrenia as they may be failing to discriminate between external stimuli and the background activity of their brain. A problem with this theory is that it does not let off wherefore symptoms improve only gradually when a f orbearing is victorious appropriate medicat! ion, although these drugs have an immediate effect on dopamine levels in the brain. Therefore this commode immoral that dopamine is not the ONLYY cause and as a result this can mean that this theory is seen as reductionist. It can also be seen as simplistic as it does not take into account of the serotonin and noradrenalin. And lastly it is only a correlational demand and so it only shows us...If you want to get a skilful essay, prepare it on our website:
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